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mcq 01/02/2012

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1 mcq 01/02/2012 on Wed Feb 01, 2012 9:09 am

avijitprusty

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protein synthesis is the process whereby DNA encodes for the production of amino acids and proteins.
In this process what is a unit of three nucleotides on the mRNA called?

a) ribozyme

b) antiribozyme

c) base-pair

d) codon

e) anticodon

2 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:09 am

avijitprusty

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CORRECT ANSWER: D

3 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:10 am

avijitprusty

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The coding mRNA sequence can be described as a unit of three nucleotides called a codon.The ribosome binds to the mRNA at the start codon (AUG) that is recognized only by the initiator tRNA. The ribosome proceeds to the elongation phase of protein synthesis. During this stage, complexes, composed of an amino acid linked to tRNA, sequentially bind to the appropriate codon in mRNA by forming complementary base pairs with the tRNA anticodon. The ribosome moves from codon to codon along the mRNA. Amino acids are added one by one, translated into polypeptidic sequences dictated by DNA and represented by mRNA. At the end, a release factor binds to the stop codon, terminating translation and releasing the complete polypeptide from the ribosome.

4 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:11 am

avijitprusty

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A 55 year old white female has a long history of red lesions with silvery scales on her knees and elbow. She has scaly lesions on her scalp as well. She denies having any itching associated with the lesions. A skin biopsy is done because of another condition that she has developed. The pathologist comments that there is retention of the nuclei in the stratum corneum. What is this correct term for this phenomenon?

a) hyperkeratosis

b) acanthosis

c) spongiosis

d) parakeratosis

e) keratosis

5 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:11 am

avijitprusty

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CORRECT ANSWER: D

6 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:12 am

avijitprusty

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Parakeratosis indicates that the cells in the stratum corneum have retained their nuclei. This is seen in conditions with rapid keratin formation, such as psoriasis. Hyperkeratosis (choice a) is an increase in the stratum corneum.Acanthosis (choice b) is hyperplasia of the stratum spinosum. Spongiosis (choice c) is edema in the epidermis. Keratosis (choice e) is a well defined lesion of the epidermis with an increase the stratum corneum.

7 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:14 am

avijitprusty

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A 30-year-old pregnant woman complains to her physician of feeling very tired during her pregnancy. A complete blood count with differential reveals a hematocrit of 30%, with hypersegmented neutrophils and large, hypochromic red cells. Deficiency of which of the following would be most likely to produce these findings?

a) Ascorbic acid

b) Calcium

c) Copper

d) Folate

e) Iron

8 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:15 am

avijitprusty

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CORRECT ANSWER: D

9 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:16 am

avijitprusty

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The patient has a megaloblastic anemia, which can be due to deficiency of folate or B12. Pregnancy increases the need for folate and other nutrients used by both baby and mother

10 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:18 am

avijitprusty

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Which of the following would shift the oxygen-hemoglobin dissociation curve to the right?

a) Carbon monoxide poisoning

b) Decreased PCO2

c) Decreased pH

d) Decreased temperature

e) Decreased 2,3-DPG

11 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:18 am

avijitprusty

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CORRECT ANSWER: C

12 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:18 am

avijitprusty

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The correct answer is C. The loading of O2 is facilitated when the oxygen dissociation curve shifts to the left, and the unloading of O2 is facilitated when the oxygen dissociation curve shifts to the right. A good way to remember the conditions that promote dissociation of O2 is to think of exercising muscle, which has decreased pH (choice C) because of the accumulation of lactic acid, increased PCO2 (compare with choice B) because of the increased rate of aerobic metabolism, increased temperature (compare with choice D), and increased 2,3-DPG (2,3-diphosphoglycerate; compare with choice E) because of increased glycolysis. Carbon monoxide poisoning (choice A) left-shifts the oxygen dissociation curve, which interferes with the unloading of O2. Carbon monoxide also strongly binds to available sites on hemoglobin.

13 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:19 am

avijitprusty

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What specific part of the eye is mainly responsible for acute vision ?

a) zonnule of Zinn

b) limbus

c) optic disc

d) macula

e) fovea

14 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:20 am

avijitprusty

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CORRECT ANSWER: E

15 Re: mcq 01/02/2012 on Wed Feb 01, 2012 9:20 am

avijitprusty

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The fovea lies slightly below and to one side of the optic disk. It is found in the centre of a shallow depression or pit (the macula). Only cones are present at the fovea, which is an area approximately 0.2 mm in diameter: all other parts of the retina including blood vessels are pushed aside. The cones here have individual connections with the bipolar and ganglion cells, hence the fovea gives us our most sensitive and acute vision.

16 Re: mcq 01/02/2012 on Wed Feb 01, 2012 4:53 pm

avijitprusty

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A patient who has suffered severe chest trauma in an automobile accident is found to have fluid in the right pleural space. A thoracentesis reveals the presence of chylous fluid in the pleural space, suggesting a rupture of the thoracic duct. In which regions of the thorax is the thoracic duct found?

a) Anterior and middle mediastinum

b) Anterior and superior mediastinum

c) Middle and posterior mediastinum

d) Middle and superior mediastinum

e) Posterior and superior mediastinum

17 Re: mcq 01/02/2012 on Wed Feb 01, 2012 4:53 pm

avijitprusty

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CORRECT ANSWER: E

18 Re: mcq 01/02/2012 on Wed Feb 01, 2012 4:53 pm

avijitprusty

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The mediastinum is divided into four regions. The region above the manubriosternal junction (level of fourth thoracic vertebra) is the superior mediastinum. The region below the manubriosternal junction is divided into the anterior mediastinum (anterior to the pericardium), the middle mediastinum (within the pericardium), and the posterior mediastinum (posterior to the pericardium). The thoracic duct enters the thorax through the aortic hiatus of the diaphragm. At this point it lies in the posterior mediastinum, the region posterior to the pericardium. As it ascends through the thorax and passes the level of the fourth thoracic vertebra, it enters the superior mediastinum. The anterior mediastinum (choices A and B) contains the thymus and fatty connective tissue. The middle mediastinum (choices A, C, and D) contains the heart and the roots of the great vessels. In addition to the thoracic duct, the superior mediastinum (choices B, D, and E) contains the ascending aorta, aortic arch, branches of the aortic arch, descending aorta, superior vena cava, brachiocephalic veins, thymus, trachea and esophagus. In addition to the thoracic duct, the posterior mediastinum (choices C and E) contains the descending aorta, azygos vein, hemiazygos vein and the esophagus

19 Re: mcq 01/02/2012 on Wed Feb 01, 2012 5:03 pm

avijitprusty

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A medical student is learning to take an ECG and inadvertently reverses the correct position right arm and left arm electrodes. This is most likely to result in

a) no EKG tracing

b) inversion of lead I

c) inversion of lead III

d) delta waves

e) all leads are inverted

20 Re: mcq 01/02/2012 on Wed Feb 01, 2012 5:03 pm

avijitprusty

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CORRECT ANSWER: B

21 Re: mcq 01/02/2012 on Wed Feb 01, 2012 5:04 pm

avijitprusty

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The most common error in frontal plane recording results from reversal of two of the electrodes. One example is reversal of the right and left arm electrodes In this instance, lead I appears inverted, leads II and III are reversed, leads aVR and aVL are reversed, and lead aVF is correct.

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